The National Down Syndrome Society (NDSS) Health and Wellness Program promotes improved health and wellbeing for all individuals with Down syndrome. Through collaboration with NDSS affiliate organizations, Down syndrome clinics, researchers, government agencies, and other key stakeholders, NDSS develops tailored and accessible resources for individuals with Down syndrome, families, and caregivers. Addressing topics across the lifespan from prenatal diagnosis to aging adults, NDSS offers guides, one-pagers, online resources, and conferences to provide information and support to the Down syndrome community.